Congenital myasthenic syndrome (CMS)

LABOKLIN Service ID: 8206

Congenital myasthenic syndrome (CMS) is a inherited neuromuscular disorder in dogs. It leads to a generalized muscle weakness that becomes more pronounced after physical exertion, stress, or excitement.
Affected puppies often show first symptoms at just a few weeks of age – in some cases as early as the second week of life. The dogs tire quickly, their movements become unsteady, and they increasingly struggle to support their own body weight.

Method

sequencing

Breed list

Australian-Labradoodle (Cobberdog), Golden Retriever, Goldendoodle, Heideterrier, Jack Russell Terrier, Labradoodle, Labrador Retriever, Old Danish Pointing Dog, Parson Russell Terrier

Heredity

autosomal recessive

Duration

1 - 2 weeks after arrival of the samples in the lab