Familial nephropathy (FN)

LABOKLIN Service ID: 8192

The Familial or Hereditary nephropathy (FN) is a juvenile-onset fatal kidney disease. The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.

Method	sequencing
Breed list	English Springer Spaniel, Samoyed
Heredity	autosomal recessive English Springer Spaniel; X chromosomal recessive in Samoyed
Duration	1 - 2 weeks after arrival of the sample in the lab