Progressive retinal atrophy (dominant PRA)

LABOKLIN Service ID: 8355

Unlike most of the other known types of PRA, PRA in these two breeds is autosomal dominant. Therefore, there are no carriers. Dogs are either free or affected. Bullmastiffs and English Mastiffs are affected by the late-onset form of PRA. The loss of vision occurs relatively late and thus often goes unnoticed at first. As blindness is only recognised when the dog is already several years old, it is important to know before breeding whether or not the respective dog is affected.

Method	sequencing
Breed list	Bullmastiff, Mastiff
Heredity	autosomal dominant
Duration	1 - 2 weeks after arrival of the sample in the lab