Primary lens luxation (PLL)
LABOKLIN Service ID: 8226
The zonula fibres secure the position of the lens. Dogs affected from PLL have painful glaucomas and blindness due to a dislocation of the lens due to a breakdown or disintegration of the zonula fibres. PLL can be inherited or acquired. Therefore the disease might also affect genetically free dogs. First clinical signs of the inherited form of PLL are detectable at the very young age of 20 months. A complete lens luxation typically occurs at the age of 3 to 8 years.
| Method | TaqMan SNP assay |
| Breed list | American Eskimo Dog, American Hairless Terrier, Australian Cattle Dog, Chinese Crested Dog, Danish-Swedish Farmdog, Fox Terrier, German Hunting Terrier, Italian Volpino, Jack Russell Terrier, Lakeland Terrier, Lancashire Heeler, Lucas Terrier, Miniature Bull Terrier, Norfolk Terrier, Norwich Terrier, Parson Russell Terrier, Patterdale Terrier, Pug, Rat Terrier, Sealyham Terrier, Teddy Roosevelt Terrier, Tenterfield Terrier, Tibetan Terrier, Toy Fox Terrier, Welsh Terrier, Westfalen Terrier, Yorkshire Terrier |
| Heredity | autosomal recessive; In most cases heterozygous carriers are healthy. However, it is estimated that about 2 – 20% of the carriers will develop PLL. |
| Duration | 3 - 5 days after arrival of the sample in the lab |