Junctional epidermolysis bullosa (JEB)

LABOKLIN Service ID: 8198

JEB (Junctional epidermolysis bullosa) is a blistering disorder of the skin and mucous membranes in which tissue separation occurs within the lamina lucida of the basement membrane zone at the dermal-epidermal junction. Affected dogs show erosion and encrustation in the field of the balls, knees, elbows, ankle joints, carpal bones, hips, lips and tongue.

Method	TaqMan SNP assay, if necessary sequencing
Breed list	German Short-haired Pointing Dog
Heredity	autosomal recessive; the genetic test detects a SNP mutation that is inherited together with the responsible mutation.
Duration	3 - 5 days after arrival of the sample in the lab (in case of sequencing 1-2 weeks)