Junctional epidermolysis bullosa (JEB)
LABOKLIN Service ID: 8198
JEB (Junctional epidermolysis bullosa) is a blistering disorder of the skin and mucous membranes in which tissue separation occurs within the lamina lucida of the basement membrane zone at the dermal-epidermal junction. Affected dogs show erosion and encrustation in the field of the balls, knees, elbows, ankle joints, carpal bones, hips, lips and tongue.
| Method | TaqMan SNP assay, if necessary sequencing |
| Breed list | German Short-haired Pointing Dog |
| Heredity | autosomal recessive; the genetic test detects a SNP mutation that is inherited together with the responsible mutation. |
| Duration | 3 - 5 days after arrival of the sample in the lab (in case of sequencing 1-2 weeks) |