Late onset ataxia (LOA)

Late onset ataxia (LOA)

LABOKLIN Service ID: 8493

This disease is caused by a mutation in the calcium activated neutral proteinase 1 (CAPN1)-gene. Affected dogs will show first indications of the ataxia at the age of 6-12 months. First clinical signs are loss of balance and minor incoordination of gait while later symptoms can be a progressive incoordination or a complete loss of mobility.