Protein losing nephropathy (PLN)
LABOKLIN Service ID: 8492
Hereditary PLN starts with a hidden proteinuria in midlife. The disease can proceed mildly and stay steady for years. In some cases severe complications like kidney failure or thromboses occur. Risk assessment for PLN is possible due to genetic testing, now. Nevertheless, starting point and development of symptoms vary hugely and are supposed to depend on enviromental factors and modifying genes. Additionally, aquired forms of PLN disease can not be detected by the genetic test.
| Method | TaqMan SNP assay |
| Breed list | Airedale Terrier, Irish Soft Coated Wheaten Terrier |
| Heredity | Heterozygous dogs possess medium risk, homozygous affected dogs possess high risk to develop symptoms of the disease. |
| Duration | 3 - 5 days after arrival of the sample in the lab |