Narcolepsy

LABOKLIN Service ID: 8067

Narcolepsy is a disabling sleep disorder affecting humans and animals. The disease is characterized by daytime sleepiness, cataplexy and striking transitions from wakefulness into REM sleep. A mutation in the gene encoding the receptor for hypocretin (orexin) receptor 2 was identified as the cause for canine narcolepsy.

Method

sequencing (Dachshund, Doberman), TaqMan SNP assay (Labrador Retriever)

Breed list

Dachshund (Dackel), Dobermann, Labrador Retriever, Long-Haired Dachshund, Short-Haired Dachshund, Wire-Haired Dachshund

Heredity

autosomal recessive

Duration

1 - 2 weeks after arrival of the sample in the lab (Dachshund, Doberman), 3 - 5 days (Labrador Retriever)