Primary open angle glaucoma and lens luxation (POAG/PLL)

LABOKLIN Service ID: 8641

A primary open angle glaucoma (POAG) is a genetic dysfunction of the connectiv tissue in the eye. Thereby, the aqueous fluid is blocked and the pressure of the eyeball rises. Ultimately, the optic nerve and the retina are damaged leading from partial to complete blindness.
Symptoms include widened pupils, red eyeballs, cloudy cornea and increased eye pressure. Raising eye-pressure causes pain, the dog loses its appetite, scratches the eyes, rubs its head on walls and exhibits aggressive behaviour. The dysfunction of the connective tissue often causes a dislocation of the lens (PLL), too.
Usually, affected dogs show first symptoms at the age of 4-6 years.

Method	TaqMan SNP assay
Breed list	Shar Pei
Heredity	autosomal recessive
Duration	3 - 5 days after arrival of the sample in the lab