Progressive retinal atrophy (cord1/crd4-PRA)

LABOKLIN Service ID: 8128

The “cone-rod” dystrophy is a variant of the progressive retinal atrophy leading to degeneration of the retina.
In contrast to rod-cone dystrophies, where rod cells are affected first and the following degeneration of the cone cells results in complete blindness of the dog, cone-rod dystrophies are characterised by the relatively early loss of cone photoreceptors.
The first ophthalmoscopic signs may appear at the age of six month. However, some genetically affected dogs never develop clinical symptoms during their life.
The correlation between the known genetic variant and the symptoms of the disease is a matter of an ongoing scientific debate.

Method	FLP
Breed list	Beagle, Bolonka Zwetna, Clumber Spaniel, Curly Coated Retriever, Dachshund (Dackel), English Springer Spaniel, French Bulldog, Long-Haired Dachshund, Short-Haired Dachshund, Wire-Haired Dachshund
Heredity	autosomal recessive
Duration	1 - 2 weeks after arrival of the sample in the lab