Haemophilia A (factor VIII deficiency)
LABOKLIN Service ID: 8689
The underlying pathomechanism of Haemophilia A is a lack or decreased activity of factor VIII that plays a critical role in the coagulation cascade. Affected dogs present with hemorrhage that can vary from mild to severe depending on the degree of the disease. The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.
| Method | sequencing (Boxer, Old English Sheepdog, Labrador Retriever); |
| Breed list | Boxer, German Shepherd Dog, Labrador Retriever, Old English Sheepdog, Rhodesian Ridgeback |
| Heredity | X chromosomal recessive |
| Duration | 1 - 2 weeks after arrival of the sample in the lab (Boxer, Old English Sheepdog, Labrador Retriever, Rhodesian Ridgeback); |