Epidermolytic hyperkeratosis (EHK)

LABOKLIN Service ID: 8311

This disease is caused by a mutation in the KRT10 gene. The keratin defect leads to superficial, mild, plantar epidermolytic hyperkeratosis with epidermal fragility. Affected dogs show clinical signs from birth through adulthood. In adults clinical lesions become hyperpigmented and remain static.

Method	sequencing
Breed list	Norfolk Terrier
Heredity	autosomal recessive
Duration	1 - 2 weeks after arrival of the sample in the lab