Hypomyelination/Shaking puppy syndrome (SPS)
LABOKLIN Service ID: 8443
The disease is caused by disruption of myelination in the spinal cord. Affected dogs show a generalized tremor at age of 12 to 14 days. The severity of thremor can vary between litter mates. The dogs can ambulate, but show a “hopping” gait in the hind limbs. The tremor is not present when the dogs are at rest or asleep and diminishes over time by 3 to 4 months of age.
| Method | TaqMan SNP assay (Weimaraner); |
| Breed list | English Springer Spaniel, Weimaraner |
| Heredity | autosomal recessive |
| Duration | 3 - 5 working days after arrival of the sample in the lab (Weimaraner) 1 - 2 weeks after arrival of the sample in the lab (English Springer Spaniel) |