Progressive retinal atrophy (pap-PRA1)

LABOKLIN Service ID: 8573

The progressive retinal athrophy (PRA) is an inherited eye disorder leading to a degeneration of the photoreceptor cells of the retina. Initially,a loss of function of the rod cells is observed proceeding in night blindness and decreased adaptation of vision. The PRA form in Papillons and Phalènes show a wide range in age of onset maybe due to different genetic background or environmental influences. The known genetic variant explains about 70% of PRA affected dogs. So, one assumes that at least one further mutation is involved in PRA genesis.

Method	TaqMan SNP assay
Breed list	Papillon, Phalène
Heredity	autosomal recessive
Duration	3 - 5 days after arrival of the sample in the lab