Malignant hyperthermia (MH)

LABOKLIN Service ID: 8062

Maligant hyperthermia (MH) is an inherited disorder of skeletal muscle characterized by hypercarbia, rhabdomyolysis, generalized skeletal muscle contracture, cardiac dysrhythmia, and renal failure, that develops on exposure to succinylcholine or volatile anesthetic agents. Specific interventions, including use of the calcium release channel antagonist dantrolene, are efficacious in reversing signs of the canine syndrome.

Method

TaqMan SNP assay

Heredity

autosomal dominant

Duration

3 - 5 days after arrival of the sample in the lab