Retinal dysplasia* (OSD)

LABOKLIN Service ID: 8392

Retinal folds, also called retinal dysplasia (RD), is observed in many dog breeds without any pathological consequence. However in the Labrador Retriever breed as well as in Samoyeds, Retinal Folds can be associated with a more severe syndrom, the OculoSkeletal Dysplasia (OSD). Clinical signs of OSD are skeletal malformations comprising shortened limbs (dwarfism) as well as blindness at early age. Blindness results from a partial or complete detachment of the retina and cataract due to a generalized malformation of the retina. The mode of inheritance is still not fully understood but an autosomal-dominant trait with incomplete penetrance is assumed.

Method	partnerlaboratory in Bratislava, Slovakia
Breed list	Labradoodle, Labrador Retriever
Heredity	autosomal dominant with incomplete penetrance
Duration	1 - 2 weeks after arrival of the sample in the lab