| Material | Serum 1 ml (centrifuged and separated shortly after coagulation, pipetted off) - please pay attention to the note – country-specific – on the submission form regarding the temperature during storage/transport!
- a 12-hour fasting period is recommended for omnivores and carnivores; only feed hay and straw to horses and donkeys
|
| Method | CLIA;
ELISA (cat only) |
| Species list | Dog, cat, horse, donkey, others on request |
| Duration | Reporting of results on the day the sample is received (Mon–Sat);
Cat: 2–6 working days |
| Remark | - The findings must be interpreted together with the blood glucose concentration from blood taken at the same time.
- Insulinoma dog: Blood must be taken at the time of documented hypoglycaemia (glucose < 3.3 mmol/l or 60 mg/dl). If hypoglycaemia is present, no insulin should be detectable. At this point, concentrations in the upper reference range are already considered to be inadequately elevated. Insulin concentrations in the lower reference range or below do not necessarily rule out insulinoma. If in doubt, the test should be repeated.
- Horse, donkey: Equine metabolic syndrome (EMS)/asinine metabolic syndrome (AMS): EMS/AMS leads to a disorder of carbohydrate and fat metabolism with insulin dysregulation (ID). Increased insulin secretion (partly) compensates for decreased insulin efficiency. Insulin-dysregulated horses/donkeys therefore have significantly elevated insulin concentrations. At the same time, fasting glucose is physiological (compensated) or elevated (not compensated). Further test: Oral Glucose Test with Insulin Determination and oral Karo Light Syrup® Test (see Endocrinology / Funktion Tests).
- Horse, donkey: Simultaneous measurement of the glucose concentration makes it possible to calculate the proxies
- insulin/glucose ratio
- reciprocal inverse square of insulin (RISQI) – “insulin sensitivity”
- modified insulin-to-glucose ratio (MIRG) – “β-cell function (pancreas)”
|
