| Material | Serum or EDTA plasma or heparin plasma 0.5 ml |
| Method | Photometry |
| Duration | Reporting of results on the day the sample is received (Mon–Sat) |
| Remark | - This isoenzyme of LDH is found in many kinds of tissue, especially in cardiac and skeletal muscles and in the liver; the activity of α-HBDH varies depending on the species.
- If α-HBDH in the LDH/α-HBDH ratio is disproportionately increased, it indicates possible damage of the cardiac muscle. Determination of c-Troponin I concentration has replaced the analysis of α-HBDH in case of this indication, though.
- Proportional or slight elevations of the enzyme point to other causes (e.g. liver damage, damage of skeletal muscles, haemolysis). In this case, CK and AST concentrations should be considered.
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