LABOKLIN Service ID: 6
Aspartate Aminotransferase (Glutamate Oxaloacetate Transaminase)
| Material | Serum or EDTA plasma or heparin plasma 0.5 ml |
| Method | Photometry |
| Duration | Reporting of results on the day the sample is received (Mon–Sat) |
| Remark | - AST is not organ-specific. Elevated concentrations can be caused by liver and muscle damage; it is not possible to distinguish between cardiac and skeletal muscle. A simultaneous increase in CK indicates a myogenic origin (CK activity rises rapidly and falls quickly, while AST activity rises and falls more slowly).
- Cat: AST is less sensitive to liver cell damage than ALT. If AST concentrations are elevated, CK should also be measured to differentiate from muscle damage.
- Horse:Elevated AST concentrations indicate muscle or liver lesions, depending on the accompanying parameters. CK and LDH help to determine the cause; GLDH and γ-GT are more specific to the liver.
- Cattle: The combination of AST and CK is prognostically useful in downer cows; persistently high AST concentrations with high CK concentrations indicate extensive muscle damage and a poor prognosis.
|
