Anti-Müllerian Hormone (AMH)

LABOKLIN Service ID: 2212


AMH is secreted in the granulosa cells of the maturing follicle and the Sertoli cells in the testes. It can be used to distinguish between castrated and intact animals. AMH concentrations in the questionable range may occur, for example, if residual ovarian tissue is present.

Material

Serum 0.5 ml (centrifuged and separated shortly after coagulation, pipetted off; cooled until arrival at the laboratory)

Method

Chemiluminescence assay (CLIA)

Species list

Dog, cat, rabbit, horse, male donkey, cattle, others on request

Duration

Reporting of results on the day the sample is received (Mon–Sat)

Remark

  • Possible causes of high AMH concentrations are (depending on gender): sexual malformation with the formation of granulosa cell tumours (GCTs), testicular tissue, cryptorchid testicular tissue, Sertoli cell tumours, testicular atrophy. After deslorelin implantation, significantly elevated AMH concentrations (> detection limit) are measured in male dogs within 30 days.
  • Horse: In addition to progesterone and testosterone, AMH is included in the Granulosa Cell Tumour Profile, which is useful in the diagnosis of hormonal disorders or hormone-producing ovarian tumours (granulosa-theca cell tumours) associated with behavioural changes and poor rideability in mares.