Progressive retinal atrophy (rdy-PRA)

LABOKLIN Service ID: 8469

A different form of blindness called “rod cone dysplasia”, or “rdy” has also been identified in Abyssinian and Somali cats. The mutation is a single base pair deletion in a different gene, CRX, which also results in a defective protein that is critical for eye development. Cats carrying one copy of this mutation have retarded development and degeneration of photoreceptor cells, which leads to early-onset blindness by 7 weeks of age.

Method	sequencing
Breed list	Abyssinian, Ocicat, Somali
Heredity	autosomal dominant
Duration	1 - 2 weeks after arrival of the sample in the lab