Hypotrichosis and short life expectancy

LABOKLIN Service ID: 8318

Hypertrichosis is an inherited disease in the breed of Burmese cats, caused by a mutation in the FOXN-1-gene. Affected kitten are either born bald or have a thin downy coat that falls out within a week of birth. Regrowth of a thin coat may occur within the first two months in some animals. In addition, oily and crusty skin in the facial area and anomalies of the claws, tongue and beard are other clinical symptoms. The disease also leads to stillbirths and early death cases in kittens in the first thirteen weeks of life due to impaired immune response.

Method	sequencing
Breed list	Birman (Sacred cat of Burma)
Heredity	autosomal recessive
Duration	1 - 2 weeks after arrival of the sample in the lab