| Diagnosis | Suspected Cushing’s syndrome, adrenergic/pituitary |
| Material | Saliva 3 x 0.1 ml (sample containers (Salivettes®) will be provided) |
| Execution | - 1st saliva sample collection = baseline cortisol
- Injection of 0.1 mg/kg bdw dexamethasone i.m. (i.v.) (high-dose dexamethasone suppression test)
- 2nd sample collection after 4 hours
- 3rd sample collection after 8 hours
|
| Parameter | Cortisol |
| Method | ELISA |
| Species list | Guinea pig |
| Duration | 3–5 working days |
| Assessment | - pituitary Cushing’s syndrome and/or bilateral adrenal hyperplasia: adequate suppression (as in dogs) after 4 hours, then rising again
- adrenergic Cushing’s syndrome: no suppression
|
