BRAF Comp. Subsequent Testing (2 CNA) (dog)

LABOKLIN Service ID: 517


Detection of BRAF variant V595E and detection of copy number
alterations (CNAs) 13/19 and 36/19.

Indications:

  • Urothelial carcinoma (transitional cell carcinoma) after negative BRAF mutation analysis (V595E)

    • Material

    • Urinary sediment (especially early morning urine; fluid + smear) or
    • Aspiration cytology (smears) or
    • Formalin-fixed, paraffin-embedded tissue (from previous histological examination)

    Method

    Copy number alteration (CNA)

    Species list

    Dog

    Duration

    2–7 working days

    Remark

  • Only a positive result is conclusive.
  • Reasons for negative results:
      • - It is not a urothelial (transitional cell) carcinoma.
      - The carcinoma does not have copy number alterations/BRAF mutation.
      - There were no or not enough relevant cells present in the sample.
      - There is severe (secondary) inflammation.
  • Testing for CNAs is not suitable for prostate cancer.
  • The test cannot be used for cats.