T3/T4 Antibodies

LABOKLIN Service ID: 2525

• Autoantibodies against the thyroid hormones triiodothyronine (T3) and thyroxine (T4) can lead to falsely elevated or reduced concentrations when determining total T3 and total T4.
• If such antibodies are present, it can complicate the interpretation of thyroid function tests and lead to false diagnoses (e.g. alleged hypo- or hyperthyroidism).
• The detection of T3 and T4 antibodies can be done if the laboratory findings show a discrepancy (e.g. elevated total T4 with clinically suspected hypothyroidism), if there are noticeable differences in the course of hormone diagnosis or if autoimmune thyroiditis is suspected.
• For predisposed breeds, the test is also useful as part of the breeding approval process.

Material	Serum 0.5 ml
Method	Enzyme linked immunosorbent assay (ELISA)
Species list	Dog
Duration	2–3 working days
Remark	If antibodies are detected, measuring T4/T3 using LCMS provides more reliable results in these cases.