LABOKLIN Service ID: 8418
| Material | Formalin-fixed tissue, paraffin material, air-dried stained or unstained cytological smears on slides without cover glass, lymphocyte-rich fluid, EDTA blood in case of lymphocytosis, other lymphoid material |
| Method | PCR for antigen receptor rearrangements (PARR) |
| Species list | dog, cat |
| Duration | 3–5 working days |
| Remark | This test provides the possibility
1) to confirm a suspected diagnosis (lymphoma/lymphatic leukaemia vs. reactive hyperplasia) and
2) if lymphoma/lymphatic leukaemia is present, to differentiate between T- or B-cell origin.
As only a cytological or a histological examination can reliably determine the presence of a lymphocyte population, the respective examinations are highly recommended. With regard to interpretation and limitations, please refer to the literature (e.g. Vet Clin Small Anim 43 (2013) 1331–1347). Furthermore, the results of all pre-examinations as well as the clinical picture should be included in the overall diagnosis (summary probability diagnosis).
The examination can be performed on all materials containing a sufficient number of lymphocytes (fixed and unfixed cell material/tissue/smears/EDTA blood). Cell material can also be obtained directly from the cytological smear (without cover glass) or the histological paraffin block.
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