Immunohistology

LABOKLIN Service ID: 209


Material

Formalin-fixed and/or paraffin-embedded tissue samples

Method

Microscopy (labelling with specific antibodies)

Duration

5–7 working days

Remark

Tumour diagnosis:

  • CD3/CD79a/PAX-5 in lymphoma diagnosis
  • c-KIT expression pattern in mast cell tumours
  • Ki-67 antigen as proliferation marker
  • Cox-2, prostaglandin synthesis enzyme, in tumours possibly an indicator of the effectiveness of inhibitors (NSAIDs)
  • cytokeratin, vimentin, CD18, melan-A, NSE to differentiate between epithelial/spindle cell/round cell/melanocytic tumours

    • Infection diagnosis:
  • e. g. FIP virus