Determination is particularly indicated in case of colitis.
A faecal sample at least the size of a cherry is required.
In carnivores, Clostridium perfringens enterotoxin can cause diarrhoea and vomiting of varying severity; enterotoxaemia is rare. Toxin formation is induced by antibiotic administration, stress, co-infections or especially by an unbalanced diet rich in proteins and connective tissue.
It plays an increasing role in farm animals, especially causing serious disease in calves, lambs (lamb dysentery) or suckling piglets (necrotising enteritis). Older animals are affected by clostridiosis (cattle), pulpy kidney disease (sheep), struck (sheep) or sporadic
catarrhal and haemorrhagic enteritis (pig).