Coumarin Activity
LABOKLIN Service ID: 511
The concentrations of vitamin K1, vitamin K1 epoxide and the ratio of vitamin K1 epoxide to vitamin K1 can indicate previous intoxication with coumarin derivatives.
| Material | Serum 0.5 ml (centrifuged shortly after coagulation, pipetted off; cooled until arrival at the laboratory) |
| Parameter | Vitamin K1/vitamin K1 epoxide ratio |
| Method | Liquid chromatography-mass spectrometry (LCMS) |
| Species list | Dog, cat |
| Duration | 1–2 working days |
| Remark | The test can also be performed while vitamin K is being administered. |