LABOKLIN Service ID: 8675
Indications:
- It was not possible to get a reliable histological/cytological diagnosis.
- Screening for transitional cell carcinoma in certain predisposed terrier breeds (e.g. Scottish Terrier, Fox Terrier, Jack Russell Terrier, West Highland White Terrier)
- Difficult patient
| Material | If urinary bladder/urethral carcinoma (transitional cell carcinoma) is suspected: - urinary sediment (especially early morning urine; fluid + smear)
- aspiration cytology (smears)
biopsies (formalin-fixed)
If prostate carcinoma is suspected: - smears rich in cells
- biopsies (formalin-fixed)
- tissue (embedded in paraffin, from preliminary histology)
|
| Method | droplet digital PCR |
| Species list | dog |
| Duration | 3 - 5 days |
| Remark | Detection of BRAF variant V595E.
Only a positive result is conclusive.
Reasons for negative results: - The transitional cell/prostate carcinoma is not caused by BRAF mutation (approx. 30 – 50% of these carcinomas – depending on the breed).
- There were no mutated cells present in the sample.
- It is not a transitional cell/prostate carcinoma.
The test cannot be used for cats. |
