Neuronal ceroid lipofuscinosis (NCL)

LABOKLIN Service ID: 8396

NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction.
The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.

Method	TaqMan SNP assay, if necessary sequencing
Breed list	American Staffordshire Terrier
Heredity	autosomal recessive
Duration	3 - 5 days after arrival of the sample in the lap, in case of sequencing 1 - 2 weeks