LABOKLIN Service ID: 667
The profile supports a structured, pathophysiologically based investigation of disorders of calcium and phosphate metabolism.
| Material | Serum 1 ml (centrifuged and separated shortly after coagulation, pipetted off)
AND 1 ml serum (collected without air (vacutainer system)) - Please pay attention to the note – country-specific! – on the submission form regarding the temperature during storage/transport!
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| Parameter | Parathormone (PTH), vitamin D (25OH), calcium, ionised calcium, phosphate
The determination of PTHrP concentration is currently included in the profile for canine samples only. |
| Duration | 1–5 working days |
| Remark | - The PTH concentration should be assessed in relation to calcium/ionised Calcium (+ phosphate if applicable).
- In cases of hypercalcaemia, a PTH concentration that is within or exceeds the reference range should be considered inadequately elevated. Secondary renal hyperparathyroidism should be ruled out.
- Parathormone (rP) supports the identification of paraneoplastic hypercalcaemia (e.g. lymphoma, anal sac carcinoma in dogs).
- Phosphate and vitamin D (25OH) are used to differentiate between secondary renal hyperparathyroidism and vitamin D-induced hypercalcaemia.
- In cats, idiopathic hypercalcaemia is the most common form; it is less common as a secondary consequence of chronic kidney disease (CKD).
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