LABOKLIN Service ID: 666
The profile supports a structured, pathophysiologically based investigation of disorders of calcium and phosphate metabolism.
| Material | serum 1 ml and EDTA plasma 1 ml (centrifuged shortly after coagulation (serum) or immediately after collection (plasma), pipetted and at least refrigerated – preferably frozen) |
| Parameter | parathormone (PTH), parathormone (rP), vitamin D (25OH), calcium, phosphate |
| Species list | dog, cat |
| Remark | - The PTH concentration should be assessed in relation to calcium/ionised Calcium (+ phosphate if applicable).
- In cases of hypercalcaemia, a PTH concentration that is within or exceeds the reference range should be considered inadequately elevated. Secondary renal hyperparathyroidism should be ruled out.
- Parathormone (rP) supports the identification of paraneoplastic hypercalcaemia (e.g. lymphoma, anal sac carcinoma in dogs).
- Phosphate and vitamin D (25OH) are used to differentiate between secondary renal hyperparathyroidism and vitamin D-induced hypercalcaemia.
- In cats, idiopathic hypercalcaemia is the most common form; it is less common as a secondary consequence of chronic kidney disease (CKD).
- The Hypercalcaemia Profile and Calcium Ionized can be requested together via test number 667. In this case, a serum or heparin plasma tube collected under air exclusion is also to be sent.
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