{"id":1416933,"date":"2022-01-05T16:08:44","date_gmt":"2022-01-05T15:08:44","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/infectious-diseases-pathogens-and-antibody-detection\/viruses\/lymphocytic-choriomeningitis-virus-lcmv\/"},"modified":"2024-11-13T12:54:06","modified_gmt":"2024-11-13T11:54:06","slug":"lymphocytic-choriomeningitis-virus-lcmv","status":"publish","type":"page","link":"https:\/\/laboklin.com\/se\/products\/infectious-diseases-pathogens-and-antibody-detection\/viruses\/lymphocytic-choriomeningitis-virus-lcmv\/","title":{"rendered":"Lymphocytic Choriomeningitis Virus (LCMV)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<h3>Diagnostic spectrum<\/h3><div class=\"vc_tta-panels-container\"><div class=\"vc_tta-panels\"><li class=\"menu-item sub-page\"><a href=\"https:\/\/laboklin.com\/se\/products\/infectious-diseases-pathogens-and-antibody-detection\/viruses\/lymphocytic-choriomeningitis-virus-lcmv\/lymphocytic-choriomeningitis-virus-lmcv-antibodies\/\">Lymphocytic Choriomeningitis Virus (LMCV) - Antibodies<\/a><\/li><\/div><\/div>[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1641395358433{margin-top: 20px !important;}&#8221;][vc_column][vc_column_text]* Partner laboratory<\/p>\n<h3><div class=\"gap\" style=\"line-height: 20px; height: 20px;\"><\/div><\/h3>\n<h3>General information<\/h3>\n<p>The main reservoir of LCMV, which belongs to the arenaviruses, is the house mouse. Cells infected with LCMV express antigens and are recognised by cytotoxic T lymphocytes. This lymphocyte activity also makes the blood-brain barrier permeable resulting in meninges and neurons being damaged.<\/p>\n<p>Infection of adult\u00a0<b><strong>mice<\/strong><\/b>\u00a0leads to choriomeningitis. In contrast, an intrauterine or neonatal infection generally causes an asymptomatic chronic carrier state in mice, with such animals forming immune complexes in the course of their lifetime that lead to glomerulonephritis. In\u00a0<b><strong>guinea pigs\u00a0<\/strong><\/b>and\u00a0<b><strong>hamsters<\/strong><\/b>, LCMV infections often progress subclinically, however, conjunctivitis, blepharitis, respiratory symptoms, tremor, seizures and paralysis have been described. LCMV is transmitted diaplacentally and with all secretions and excretions.<\/p>\n<p>In humans, LCMV rarely leads to choriomeningitis; the infection is usually asymptomatic or shows mild, flu-like symptoms. An infection in the second part of pregnancy can cause severe foetal damage.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1641395358433{margin-top: 20px !important;}&#8221;][vc_column][vc_column_text]* Partner laboratory General information The main reservoir of LCMV, which belongs to the arenaviruses, is the house mouse. Cells infected with LCMV express antigens and are recognised by cytotoxic T lymphocytes. This lymphocyte activity also makes the blood-brain barrier permeable resulting in meninges and neurons being damaged. Infection of adult\u00a0mice\u00a0leads&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1383221,"menu_order":300,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1416933","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/pages\/1416933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/comments?post=1416933"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/pages\/1416933\/revisions"}],"predecessor-version":[{"id":1523241,"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/pages\/1416933\/revisions\/1523241"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/pages\/1383221"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/se\/wp-json\/wp\/v2\/media?parent=1416933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}