Foal immunodeficiency syndrome (FIS)

LABOKLIN Service ID: 8454

Foal immunodeficiency syndrome (FIS) is a genetic disease that affects two related British pony breeds, namely the Fell and the Dales. Foals with FIS appear to be normal at birth but within a few weeks develop evidence of infection such as diarrhoea, pneumonia, etc. The infections are resistant to treatment, and the foals die or are euthanized before three months of age. The foals also suffer from a severe progressive anemia.

Method

sequencing

Breed list

Dales pony, Fell pony

Heredity

autosomal recessive

Duration

1 - 2 weeks after arrival of the sample in the lab