{"id":1433812,"date":"2020-10-16T11:36:27","date_gmt":"2020-10-16T09:36:27","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/genetics\/hereditary-diseases\/dog\/dandy-walker-like-malformation-dwlm\/"},"modified":"2022-11-22T14:23:13","modified_gmt":"2022-11-22T13:23:13","slug":"dandy-walker-like-malformation-dwlm","status":"publish","type":"page","link":"https:\/\/laboklin.com\/no\/products\/genetics\/hereditary-diseases\/dog\/dandy-walker-like-malformation-dwlm\/","title":{"rendered":"Dandy-Walker-like malformation (DWLM)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Dandy-Walker-like malformation (DWLM)<\/h3><p><span>LABOKLIN Service ID: 8260<\/span><\/p><p class=\"bodytext\">Workgroups of Prof. Andrea Fischer from the university of Munich and of Prof. Tosso Leeb from the university of Bern found a causative mutation for cerebellar hypoplasia in dogs for the first time: A mutation in the VLDLR-gene is responsible for the so called Dandy-Walker-like malformation (DWLM) found in Eurasian dogs. DWLM as a disease is caused by a malformation of the cerebellum. Symptoms include various forms of ataxia and commence at the age of 5-6 weeks. Affected dogs exhibit wobbly gait, loss of balance or periodic reoccurring collapses. Epileptic seizures were described in some cases as well.<\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">TaqMan SNP assay<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Eurasian<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">autosomal recessive<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">3 - 5 days after arrival of the sample<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Dandy-Walker-like malformation (DWLM)LABOKLIN Service ID: 8260Workgroups of Prof. Andrea Fischer from the university of Munich and of Prof. Tosso Leeb from the university of Bern found a causative mutation for cerebellar hypoplasia in dogs for the first time: A mutation in the VLDLR-gene is responsible for the so called Dandy-Walker-like malformation (DWLM) found in Eurasian&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1419948,"menu_order":197,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1433812","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/pages\/1433812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/comments?post=1433812"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/pages\/1433812\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/pages\/1419948"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/no\/wp-json\/wp\/v2\/media?parent=1433812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}