{"id":1520991,"date":"2024-10-11T15:18:46","date_gmt":"2024-10-11T13:18:46","guid":{"rendered":"https:\/\/laboklin.com\/?page_id=1520991"},"modified":"2024-10-11T15:18:59","modified_gmt":"2024-10-11T13:18:59","slug":"primary-immunodeficiency-type-2-pips2","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fr\/prestations\/genetique\/maladies-hereditaires\/dog\/primary-immunodeficiency-type-2-pips2\/","title":{"rendered":"Primary Immunodeficiency type 2 (PIPS2)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Primary immunodeficiency type 2 (PIPS2)<\/h3><p><span>LABOKLIN Service ID: 8937<\/span><\/p><p class=\"bodytext\">In the breed Cavalier King Charles Spaniel, a variant in the CARMIL2 gene was identified to cause Primary Immunodeficiency with increased susceptibility for respiratory pathogens. Affected dogs were infected with the pathogens Pneumocystis or Bordetella bronchiseptica and showed symptoms of refractory pneumonia.  Gastrointestinal parasitism and chronic diarrhea, as well as skin disease and abscess formation were reported in the medical history of the affected dogs. <\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">sequencing<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Cavalier King Charles Spaniel, Cavapoo, King Charles Spaniel<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">autosomal recessive<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">1 - 2 weeks after arrival of the sample<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Primary immunodeficiency type 2 (PIPS2)LABOKLIN Service ID: 8937In the breed Cavalier King Charles Spaniel, a variant in the CARMIL2 gene was identified to cause Primary Immunodeficiency with increased susceptibility for respiratory pathogens. Affected dogs were infected with the pathogens Pneumocystis or Bordetella bronchiseptica and showed symptoms of refractory pneumonia. Gastrointestinal parasitism and chronic diarrhea, as&hellip;<\/p>\n","protected":false},"author":31,"featured_media":0,"parent":1419953,"menu_order":117,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1520991","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1520991","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/comments?post=1520991"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1520991\/revisions"}],"predecessor-version":[{"id":1520999,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1520991\/revisions\/1520999"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1419953"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/media?parent=1520991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}