{"id":1433228,"date":"2022-09-06T10:55:11","date_gmt":"2022-09-06T08:55:11","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/genetics\/hereditary-diseases\/dog\/l-2-hydroxyglutaric-aciduria-l2hga\/"},"modified":"2022-09-06T10:55:11","modified_gmt":"2022-09-06T08:55:11","slug":"l-2-hydroxyglutaric-aciduria-l2hga","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fr\/prestations\/genetique\/maladies-hereditaires\/dog\/l-2-hydroxyglutaric-aciduria-l2hga\/","title":{"rendered":"L-2-hydroxyglutaric aciduria (L2HGA)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">L-2-hydroxyglutaric aciduria (L-2-HGA)<\/h3><p><span>LABOKLIN Service ID: 8125<\/span><\/p><p class=\"bodytext\">L-2-HGA (L-2-hydroxyglutaric aciduria) is a neurometabolic disorder characterised by elevated levels of L-2-hydroxyglutaric acid in urine, plasma and cerebrospinal fluid. L-2-HGA affects the central nervous system, with clinical signs usually apparent between 6 months and one year (although they can appear later). L-2-HGA produces a variety of neurological deficits, including psychomotor retardation, seizures and ataxia. Symptoms are \"wobbly\" gait, tremors, muscle stiffness as a result of exercise or excitement and altered behaviour.<\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">TaqMan SNP assay (Staffordshire Bull Terrier); sequencing (Yorkshire Terrier)<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Staffordshire Bull Terrier, Yorkshire Terrier<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">autosomal recessive<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">3 - 5 days after arrival of the sample in the lab (Staffordshire Bull Terrier);\r\n1-2 weeks after arrival of the sample in the lab (Yorkshire Terrier)<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>L-2-hydroxyglutaric aciduria (L-2-HGA)LABOKLIN Service ID: 8125L-2-HGA (L-2-hydroxyglutaric aciduria) is a neurometabolic disorder characterised by elevated levels of L-2-hydroxyglutaric acid in urine, plasma and cerebrospinal fluid. L-2-HGA affects the central nervous system, with clinical signs usually apparent between 6 months and one year (although they can appear later). L-2-HGA produces a variety of neurological deficits, including&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1419953,"menu_order":144,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1433228","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1433228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/comments?post=1433228"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1433228\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1419953"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/media?parent=1433228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}