{"id":1432273,"date":"2022-09-06T10:55:09","date_gmt":"2022-09-06T08:55:09","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/genetics\/hereditary-diseases\/dog\/spinal-dysraphism-ntd\/"},"modified":"2022-11-22T13:05:50","modified_gmt":"2022-11-22T12:05:50","slug":"spinal-dysraphism-ntd","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fr\/prestations\/genetique\/maladies-hereditaires\/dog\/spinal-dysraphism-ntd\/","title":{"rendered":"Spinal dysraphism (NTD)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Spinal dysraphism (NTD)<\/h3><p><span>LABOKLIN Service ID: 8605<\/span><\/p><p class=\"bodytext\">Neural tube defects result from abnormal closure or development of the neuronal tube during embryogenesis. In the Weimaraner breed, a mutation of the regulatory  homebox gene NKX2-8, which is expressed in the developing tube, could be found to be associated with the neural tube defect, termed spinal dysraphism. The spinal dysraphism is a non-progressiv ataxia and is characterised by the following symptoms: abnormal hair streams along the back, kinked tails, scoliosis in the lumbar spinal region, paraparesis, \u201cbunny-hopping\u201d, crouched stance.<\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">sequencing<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Weimaraner<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">autosomal recessive<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">1 - 2 weeks after arrival of the sample in the lab<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Spinal dysraphism (NTD)LABOKLIN Service ID: 8605Neural tube defects result from abnormal closure or development of the neuronal tube during embryogenesis. In the Weimaraner breed, a mutation of the regulatory homebox gene NKX2-8, which is expressed in the developing tube, could be found to be associated with the neural tube defect, termed spinal dysraphism. The spinal&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1419953,"menu_order":56,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1432273","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1432273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/comments?post=1432273"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1432273\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1419953"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/media?parent=1432273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}