{"id":1431782,"date":"2022-09-06T10:55:09","date_gmt":"2022-09-06T08:55:09","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/genetics\/hereditary-diseases\/dog\/neuronal-ceroid-lipofuscinosis-ncl\/"},"modified":"2025-12-17T14:38:39","modified_gmt":"2025-12-17T13:38:39","slug":"neuronal-ceroid-lipofuscinosis-ncl","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fr\/prestations\/genetique\/maladies-hereditaires\/dog\/neuronal-ceroid-lipofuscinosis-ncl\/","title":{"rendered":"Neuronal ceroid lipofuscinosis (NCL)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Neuronal ceroid lipofuscinosis (NCL) <\/h3><p><span>LABOKLIN Service ID: 8396<\/span><\/p><p class=\"bodytext\">NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction.<br \/>\nThe clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.<\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">TaqMan SNP assay, if necessary sequencing<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">American Staffordshire Terrier<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">autosomal recessive<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">3 - 5 days after arrival of the sample in the lap, in case of sequencing 1 - 2 weeks<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Neuronal ceroid lipofuscinosis (NCL) LABOKLIN Service ID: 8396NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction. The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1419953,"menu_order":42,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1431782","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1431782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/comments?post=1431782"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1431782\/revisions"}],"predecessor-version":[{"id":1541303,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1431782\/revisions\/1541303"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/pages\/1419953"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fr\/wp-json\/wp\/v2\/media?parent=1431782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}