{"id":1445486,"date":"2022-09-06T10:54:58","date_gmt":"2022-09-06T08:54:58","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/haematology-clin-chemistry-endocrinology\/endocrinology-tumour-markers\/t4-thyroxine\/"},"modified":"2025-11-20T10:00:34","modified_gmt":"2025-11-20T09:00:34","slug":"t4-thyroxine","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fi\/products\/haematology-clin-chemistry-endocrinology\/endocrinology-tumour-markers\/t4-thyroxine\/","title":{"rendered":"T4 (Thyroxine)"},"content":{"rendered":"

T4 (Total Thyroxine)<\/h3>

LABOKLIN Service ID: 137<\/span><\/p>


<\/p>
Material<\/strong><\/td>

serum or heparin plasma 0.5 ml or 0.4 ml in small mammals<\/p><\/td><\/tr>

Method<\/strong><\/td>

CLIA (chemiluminescence assay)<\/p><\/td><\/tr>

Species list<\/strong><\/td>

dog, cat, guinea pig, horse, cattle, camelids, others on request<\/p><\/td><\/tr>

Duration<\/strong><\/td>

Reporting of results on the day the sample is received (Mon\u2013Sat)<\/p><\/td><\/tr>

Remark<\/strong><\/td>

  • Dog<\/strong>: Most commonly used to diagnose hypothyroidism. Cave: A low T4 concentration is not necessarily associated with hypothyroidism. The assessment should be made together with TSH. rT3 can provide further information to help distinguish between non-thyroid causes of reduced T4 concentration. If the findings are inconclusive, a TRH Stimulation Test (see Endocrinology\/Funktion Tests) can be performed.<\/li>
  • Therapy monitoring for hypothyroidism in dogs<\/strong>: 4\u20136 hours after administration of thyroxine; therapy monitoring every 2\u20134 weeks until clinical stabilisation is achieved, then every 3\u20136 months. Target: middle to upper reference range.<\/li>
  • Cat<\/strong>: Most commonly used to diagnose hyperthyroidism. Elevated serum T4 concentrations indicate hyperthyroidism. T4 in the (upper) reference range does not necessarily rule out hyperthyroidism. If in doubt, a combination of determining T4, fT4 and TSH and repeat measurements can help.<\/li>
  • Therapy monitoring for hyperthyroidism in cats<\/strong>: Therapy monitoring every 2\u20134 weeks until good control is achieved, then every 3\u20136 months. Target: medium reference range. T4 concentrations that are too low should be avoided.<\/li>
  • Dog, cat<\/strong>: T4 can be determined by LCMS measurement without interference from metabolites or antibodies. This analysis can be requested via the Thyroid Mass Spectrometry profile. <\/li>
  • Small mammals<\/strong>: T4 is suitable for diagnosing hyperthyroidism. Hypothyroidism has not yet been described in small mammals.<\/li>
  • Horse<\/strong>: For very rare cases of hypothyroidism, determination of T4 and T3 followed by a TRH Stimulation Test is recommended (see Endocrinology\/Funktion Tests).<\/li><\/ul><\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"

    T4 (Total Thyroxine)LABOKLIN Service ID: 137Materialserum or heparin plasma 0.5 ml or 0.4 ml in small mammalsMethodCLIA (chemiluminescence assay)Species listdog, cat, guinea pig, horse, cattle, camelids, others on requestDurationReporting of results on the day the sample is received (Mon\u2013Sat)RemarkDog: Most commonly used to diagnose hypothyroidism. Cave: A low T4 concentration is not necessarily associated with…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1445087,"menu_order":14,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","_seopress_news_disabled":"","_seopress_video_disabled":"","_seopress_video":[],"_seopress_pro_schemas_manual":[],"_seopress_pro_rich_snippets_disable_all":"","_seopress_pro_rich_snippets_disable":[],"_seopress_pro_schemas":[],"footnotes":""},"class_list":["post-1445486","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445486","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/comments?post=1445486"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445486\/revisions"}],"predecessor-version":[{"id":1537796,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445486\/revisions\/1537796"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445087"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/media?parent=1445486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}