{"id":1445457,"date":"2022-09-06T10:54:57","date_gmt":"2022-09-06T08:54:57","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/haematology-clin-chemistry-endocrinology\/function-tests-calculation-formulas\/acth-stimulation-test-extended\/"},"modified":"2025-11-20T10:31:50","modified_gmt":"2025-11-20T09:31:50","slug":"acth-stimulation-test-extended","status":"publish","type":"page","link":"https:\/\/laboklin.com\/fi\/products\/haematology-clin-chemistry-endocrinology\/function-tests-calculation-formulas\/acth-stimulation-test-extended\/","title":{"rendered":"ACTH Stimulation Test Extended"},"content":{"rendered":"

ACTH Stimulation Test Extended<\/h3>

LABOKLIN Service ID: 2141<\/span><\/p>


<\/p>
Diagnosis<\/strong><\/td>

  • Endocrine-active adrenal neoplasia, adrenal hyperplasia<\/li>
  • Early Cushing\u2019s disease<\/li> <\/ul><\/p><\/td><\/tr>
Material<\/strong><\/td>

serum 2 x 0.5 ml<\/p><\/td><\/tr>

Execution<\/strong><\/td>

  • First blood collection = baseline value<\/li>
  • Injection of 5 \u03bcg ACTH\/kg as Cosacthen\u00ae i.v.\/i.m.<\/li>
  • Second blood collection 1 hour post ACTH injection = stimulation value<\/li><\/ul><\/p><\/td><\/tr>
Parameter<\/strong><\/td>

(2x cortisol, 2x 17-OH progesterone)<\/p><\/td><\/tr>

Species list<\/strong><\/td>

dog<\/p><\/td><\/tr>

Duration<\/strong><\/td>

2-6 days<\/p><\/td><\/tr>

Assessment<\/strong><\/td>

  • Corresponds to the basic ACTH Stimulation Test regarding the interpretation of cortisol.<\/li>
  • To clarify steroidal adrenal pathologies, cortisol and 17-OH progesterone can be determined simultaneously. This is also possible in case of questionable results when determining the cortisol level after ACTH stimulation.<\/li>
  • In dogs with physiological steroid hormone synthesis, the concentration of 17-OH progesterone increases to up to 180 ng\/dl in the ACTH stimulation test.<\/li>
  • Dogs with a possible imbalance in the synthesis, which is found, for example, in case of enzyme defects or adrenal tumours, show an increased baseline concentration and significant hyperstimulation. <\/li>
  • Dogs with pituitary-dependent hyperadrenocorticism also show hyperstimulation. If the cortisol level is also significantly increased after stimulation, it indicates classic hyperadrenocorticism.<\/li>
  • Because of the test properties, patients that are already being treated with Vetoryl\u00ae cannot be tested for 17-OH progesterone.<\/li><\/ul><\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"

    ACTH Stimulation Test ExtendedLABOKLIN Service ID: 2141Diagnosis Endocrine-active adrenal neoplasia, adrenal hyperplasia Early Cushing\u2019s disease Materialserum 2 x 0.5 mlExecutionFirst blood collection = baseline valueInjection of 5 \u03bcg ACTH\/kg as Cosacthen\u00ae i.v.\/i.m.Second blood collection 1 hour post ACTH injection = stimulation valueParameter(2x cortisol, 2x 17-OH progesterone)Species listdogDuration2-6 daysAssessmentCorresponds to the basic ACTH Stimulation Test regarding…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1444818,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1445457","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445457","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/comments?post=1445457"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445457\/revisions"}],"predecessor-version":[{"id":1537895,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1445457\/revisions\/1537895"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/pages\/1444818"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/fi\/wp-json\/wp\/v2\/media?parent=1445457"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}