Dourine is an infectious disease of equines which is transmitted during mating from horse to horse; course can be acute to chronic. Naïve reservoirs of Trypanosoma equiperdum are exclusively infected equines; mares and stallions host the pathogen in their genital secretions. Incubation time, severity and duration of disease vary markedly. Subclinical infections are possible; donkeys and mules seem to be more resistant. Clinically animals show inflammatory changes of outer genital tract with depigmentation of mucosa up to peripheral-neurologic disturbances/paralysis.

Especially in Asia and Africa still widespread; Central Europe is currently free from T. equiperdum. 

Trypanosoma evansi (dog): North Africa, Middle East, Latin America, Asia