{"id":660014,"date":"2022-09-06T10:54:57","date_gmt":"2022-09-06T08:54:57","guid":{"rendered":"https:\/\/staging.laboklin.com\/int\/acth-stimulation-test-extended"},"modified":"2025-11-20T10:31:25","modified_gmt":"2025-11-20T09:31:25","slug":"acth-stimulation-test-extended","status":"publish","type":"page","link":"https:\/\/laboklin.com\/en\/products\/haematology-clin-chemistry-endocrinology\/function-tests-calculation-formulas\/acth-stimulation-test-extended\/","title":{"rendered":"ACTH Stimulation Test Extended"},"content":{"rendered":"

ACTH Stimulation Test Extended<\/h3>

LABOKLIN Service ID: 2141<\/span><\/p>


<\/p>
Diagnosis<\/strong><\/td>

  • Suspected endocrine-active adrenal neoplasia, adrenal hyperplasia<\/li>
  • Early (subdiagnostic) Cushing\u2019s syndrome<\/li> <\/ul><\/p><\/td><\/tr>
Material<\/strong><\/td>

Serum 2 x 0.5 ml<\/p><\/td><\/tr>

Execution<\/strong><\/td>

  • First blood collection = baseline value<\/li>
  • Injection of 5 \u03bcg ACTH\/kg as Cosacthen\u00ae i.v.\/(i.m.)<\/li>
  • Second blood collection 1 hour post ACTH injection = stimulation value<\/li><\/ul><\/p><\/td><\/tr>
Parameter<\/strong><\/td>

Cortisol and 17 OH-progesterone<\/p><\/td><\/tr>

Method<\/strong><\/td>

Cortisol: Chemiluminescence assay (CLIA);
17 OH-progesterone: Liquid chromatography-mass spectrometry (LCMS)<\/p><\/td><\/tr>

Species list<\/strong><\/td>

Dog<\/p><\/td><\/tr>

Duration<\/strong><\/td>

Reporting of partial results (cortisol) on the day the sample is received (Mon\u2013Sat);
Final results after 2\u20136 working days<\/p><\/td><\/tr>

Assessment<\/strong><\/td>

A significant increase in 17 OH-progesterone while cortisol concentrations are within reference range may indicate subdiagnostic (atypical) Cushing\u2019s syndrome. However, it should be noted that the specificity is relatively low. Differential diagnoses should be excluded.<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"

ACTH Stimulation Test ExtendedLABOKLIN Service ID: 2141DiagnosisSuspected endocrine-active adrenal neoplasia, adrenal hyperplasiaEarly (subdiagnostic) Cushing\u2019s syndrome MaterialSerum 2 x 0.5 mlExecutionFirst blood collection = baseline valueInjection of 5 \u03bcg ACTH\/kg as Cosacthen\u00ae i.v.\/(i.m.)Second blood collection 1 hour post ACTH injection = stimulation valueParameterCortisol and 17 OH-progesteroneMethodCortisol: Chemiluminescence assay (CLIA);17 OH-progesterone: Liquid chromatography-mass spectrometry (LCMS)Species listDogDurationReporting of…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":660000,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-660014","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/660014","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/comments?post=660014"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/660014\/revisions"}],"predecessor-version":[{"id":1537896,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/660014\/revisions\/1537896"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/660000"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/media?parent=660014"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}