{"id":1211165,"date":"2022-09-06T10:55:11","date_gmt":"2022-09-06T08:55:11","guid":{"rendered":"https:\/\/staging.laboklin.com\/int\/fucosidosis"},"modified":"2021-12-02T09:23:07","modified_gmt":"2021-12-02T08:23:07","slug":"fucosidosis","status":"publish","type":"page","link":"https:\/\/laboklin.com\/en\/products\/genetics\/hereditary-diseases\/dog\/fucosidosis\/","title":{"rendered":"Fucosidosis"},"content":{"rendered":"

Fucosidosis<\/h3>

LABOKLIN Service ID: 8016<\/span><\/p>

Fucosidosis is a lysosomal storage disorder caused by deficiency of the enzyme \u03b1-L-fucosidase. In healthy animals, this enzyme cleaves complex proteins and lipids so that they can be metabolised. A diseased animal lacks this enzyme whereby the complex proteins and lipids are stored in diverse organs; for example in lymph nodes, pancreas, liver, kidneys, lungs and bone marrow and especially in cerebral and neural tissue. The disease in the Springer Spaniel manifests as a mainly neurological syndrome with mixed motor and mental function deficits. Affected animals show a disturbed coordination of movements, behavioural abnormalities, blindness, deafness and problems in deglutition. The disease occurs between the age of 18 months and 4 years with a progressive course and finally lethal outgoing.<\/p>
Method<\/strong><\/td>

sequencing<\/p><\/td><\/tr>

Breed list<\/strong><\/td>

English Springer Spaniel<\/p><\/td><\/tr>

Heredity<\/strong><\/td>

autosomal recessive<\/p><\/td><\/tr>

Duration<\/strong><\/td>

1 - 2 weeks after arrival of the sample in the lab<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"

FucosidosisLABOKLIN Service ID: 8016Fucosidosis is a lysosomal storage disorder caused by deficiency of the enzyme \u03b1-L-fucosidase. In healthy animals, this enzyme cleaves complex proteins and lipids so that they can be metabolised. A diseased animal lacks this enzyme whereby the complex proteins and lipids are stored in diverse organs; for example in lymph nodes, pancreas,…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1211000,"menu_order":152,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1211165","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211165","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/comments?post=1211165"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211165\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211000"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/media?parent=1211165"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}