{"id":1211102,"date":"2022-09-06T10:55:10","date_gmt":"2022-09-06T08:55:10","guid":{"rendered":"https:\/\/staging.laboklin.com\/int\/vitamin-d-dependent-rickets-vdr"},"modified":"2021-12-02T09:23:06","modified_gmt":"2021-12-02T08:23:06","slug":"vitamin-d-dependent-rickets-vdr","status":"publish","type":"page","link":"https:\/\/laboklin.com\/en\/products\/genetics\/hereditary-diseases\/dog\/vitamin-d-dependent-rickets-vdr\/","title":{"rendered":"Vitamin D dependent rickets (VDR)"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Vitamin D dependent rickets (VDR)<\/h3><p><span>LABOKLIN Service ID: 8302<\/span><\/p><p class=\"bodytext\">The hereditary form of vitamin D-dependent rickets type II is caused by a defect in the vitamin D receptor gene VDR, which makes the active hormone calcitriol unable to bind. As a consequence, calcium cannot be absorbed intestinally, which results in skeletal malformation and hypomineralization of bones during growth at a young age. Because the VDR gene is also involved in the hair growth cycle, alopecia may occur as well.<\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">sequencing<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Breed list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Pomeranian, Pomsky<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Heredity<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">unknown<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">1 - 2 weeks after arrival of the sample in the lab<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin D dependent rickets (VDR)LABOKLIN Service ID: 8302The hereditary form of vitamin D-dependent rickets type II is caused by a defect in the vitamin D receptor gene VDR, which makes the active hormone calcitriol unable to bind. As a consequence, calcium cannot be absorbed intestinally, which results in skeletal malformation and hypomineralization of bones during&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1211000,"menu_order":100,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1211102","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/comments?post=1211102"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211102\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/pages\/1211000"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/en\/wp-json\/wp\/v2\/media?parent=1211102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}