Actinobacillus pleuropneumoniae (APP)

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General information

Actinobacillus pleuropneumoniae is a gram-negative bacillus. It produces exotoxins that can destroy lung macrophages and erythrocytes. The clinical picture of APP infection is characterised by severe respiratory symptoms with significant impairment of the general condition (fever up to 42 °C). In intensive pig farming, pleuropneumonia caused by A. pleuropneumoniae is one of the most important infectious diseases. In peracute courses of the disease, it can lead to the death of the animals within 24 hours.