{"id":1428396,"date":"2022-09-06T10:54:57","date_gmt":"2022-09-06T08:54:57","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/haematology-clin-chemistry-endocrinology\/function-tests-calculation-formulas\/cortisol-creatinine-ratio\/"},"modified":"2025-11-20T10:34:40","modified_gmt":"2025-11-20T09:34:40","slug":"cortisol-creatinine-ratio","status":"publish","type":"page","link":"https:\/\/laboklin.com\/dk\/products\/haematology-clin-chemistry-endocrinology\/function-tests-calculation-formulas\/cortisol-creatinine-ratio\/","title":{"rendered":"Cortisol\/Creatinine Ratio"},"content":{"rendered":"

Cortisol\/Creatinine Ratio<\/h3>

LABOKLIN Service ID: 183<\/span><\/p>


<\/p>
Diagnosis<\/strong><\/td>

Diagnosis of Cushing\u2019s disease including differentiation between adrenal and pituitary forms.<\/p><\/td><\/tr>

Material<\/strong><\/td>

Morning urine 1 ml<\/p><\/td><\/tr>

Execution<\/strong><\/td>

  • Collection of morning urine day 1 = sample 1<\/li>
  • Collection of morning urine day 2 = sample 2 <\/li>
  • Administration of dexamethasone on day 2: orally 3 x 0.1 mg\/kg bdw throughout the day<\/li>
  • Collection of morning urine day 3 = sample 3 <\/li><\/p><\/td><\/tr>
Parameter<\/strong><\/td>

Cortisol, creatinine<\/p><\/td><\/tr>

Species list<\/strong><\/td>

dog<\/p><\/td><\/tr>

Duration<\/strong><\/td>

1 day<\/p><\/td><\/tr>

Assessment<\/strong><\/td>

  • Interpretation of the ratio of day 1 and day 2:
    < 40: Normadrenocorticism, Cushing\u2019s disease is unlikely.
    40 \u2013 60: Questionable result
    > 60: Hyperadrenocorticism is possible and should be verified by a low-dose dexamethasone test.<\/li>
  • Interpretation of the ratio of day 3:
    (An increased ratio on day 1 and day 2 is a prerequisite)
    > 50% of the average value of the first two samples indicate a cortisol-producing adrenocortical tumour. The presence of nonsuppressible pituitary Cushing\u2019s disease is possible.
    < 50% of the average value of the first two samples indicate a pituitary-dependent Cushing\u2019s disease or another disease which causes increased cortisol secretion (diabetes, stress, gastrointestinal diseases, diseases with protein loss).<\/li><\/ul><\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"

    Cortisol\/Creatinine RatioLABOKLIN Service ID: 183DiagnosisDiagnosis of Cushing\u2019s disease including differentiation between adrenal and pituitary forms.MaterialMorning urine 1 mlExecution Collection of morning urine day 1 = sample 1 Collection of morning urine day 2 = sample 2 Administration of dexamethasone on day 2: orally 3 x 0.1 mg\/kg bdw throughout the day Collection of morning urine…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1383132,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1428396","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/pages\/1428396","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/comments?post=1428396"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/pages\/1428396\/revisions"}],"predecessor-version":[{"id":1515723,"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/pages\/1428396\/revisions\/1515723"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/pages\/1383132"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/dk\/wp-json\/wp\/v2\/media?parent=1428396"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}