{"id":1418189,"date":"2022-09-06T10:54:57","date_gmt":"2022-09-06T08:54:57","guid":{"rendered":"https:\/\/staging-wp-int.laboklin.com\/products\/haematology-clin-chemistry-endocrinology\/endocrinology-tumour-markers\/thymidine-kinase\/"},"modified":"2025-11-20T10:15:20","modified_gmt":"2025-11-20T09:15:20","slug":"thymidine-kinase","status":"publish","type":"page","link":"https:\/\/laboklin.com\/ch-it\/products\/haematology-clin-chemistry-endocrinology\/endocrinology-tumour-markers\/thymidine-kinase\/","title":{"rendered":"Thymidine Kinase"},"content":{"rendered":"<h3 class=\"csc-firstHeader\">Thymidine Kinase<\/h3><p><span>LABOKLIN Service ID: 1038<\/span><\/p><p class=\"bodytext\"><br><ul><li>Thymidine kinase (TK-1) is the enzyme which helps introduce the nucleoside thymidine into the DNA by converting deoxythymidine to deoxythymidine phosphate (dTMP). It is thus essential for DNA synthesis.<\/li><li>The activity of serum thymidine kinase 1 (sTK-1) correlates closely with DNA synthesis and cell proliferation. The main indications for the determination of thymidine kinase in malignant haematopoietic neoplasms are therapy monitoring and early detection of relapse.<\/li><li><\/p><table class=\"tx-laboklinleistung-table contenttable contenttable-2\" style=\"margin-top: 35px;\"><tr><td class=\"td-0\"><strong>Material<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Serum 0.5 ml ((centrifuged and separated shortly after coagulation, pipetted off; cooled until arrival at the laboratory)<br><strong>Horse:<\/strong> also puncture fluid (chest or abdominal cavity fluid) 0.5 ml (cooled until arrival at the laboratory) (<strong>service ID: 540<\/strong>)<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Method<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Chemiluminescence assay (CLIA)<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Species list<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Dog, cat, horse, others on request<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Duration<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\">Reporting of results on the day the sample is received (Mon\u2013Sat)<\/p><\/td><\/tr><tr><td class=\"td-0\"><strong>Remark<\/strong><\/td><td class=\"td-1\"><p class=\"bodytext\"><ul><li>Thymidine kinase is mainly excreted renally. Therefore, if the concentration is increased, it is necessary to exclude impaired renal function in differential diagnosis.<\/li><li>Patients with hepatic cirrhosis may also show elevated concentrations.<\/li><li>Growing patients physiologically have higher concentrations.<\/li><li>Thymidine kinase is also included in the profiles Tumour Diagnostics Small (dog, cat, horse) and Tumour Diagnostics Large (dog).<\/li> <li><strong>Horse:<\/strong> Determination of thymidine kinase in puncture fluid is requested as a separate service.<\/li><\/ul><\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":"<p>Thymidine KinaseLABOKLIN Service ID: 1038Thymidine kinase (TK-1) is the enzyme which helps introduce the nucleoside thymidine into the DNA by converting deoxythymidine to deoxythymidine phosphate (dTMP). It is thus essential for DNA synthesis.The activity of serum thymidine kinase 1 (sTK-1) correlates closely with DNA synthesis and cell proliferation. The main indications for the determination of&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1346882,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","_seopress_news_disabled":"","_seopress_video_disabled":"","_seopress_video":[],"_seopress_pro_schemas_manual":[],"_seopress_pro_rich_snippets_disable_all":"","_seopress_pro_rich_snippets_disable":[],"_seopress_pro_schemas":[],"footnotes":""},"class_list":["post-1418189","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/pages\/1418189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/comments?post=1418189"}],"version-history":[{"count":1,"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/pages\/1418189\/revisions"}],"predecessor-version":[{"id":1537821,"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/pages\/1418189\/revisions\/1537821"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/pages\/1346882"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/ch-it\/wp-json\/wp\/v2\/media?parent=1418189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}